Quinidine hydrochloride monohydrate

SKU: orb1310777

Description

Quinidine hydrochloride monohydrate is a stereoisomer of quinine, a natural cinchona alkaloid. It functions as a broad ion channel and receptor antagonist, prolonging cardiac action potentials and reducing excitability in muscle cells. This compound is widely used in cardiovascular research, particularly for studying arrhythmia mechanisms and electrophysiology in vitro.

Research Area

Infectious Disease & Virology, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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CAS Number	6151-40-2
MW	378.89
Purity	99.68%
Formula	C₂₀H₂₇ClN₂O₃
SMILES	O.Cl.[H][C@@]1(C[C@@H]2CCN1C[C@@H]2C=C)[C@@H](O)c1ccnc2ccc(OC)cc12
Target	Parasite,Potassium Channel,Sodium Channel
Solubility	DMSO:32.5 mg/mL (85.78 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.28 mM)

Bioactivity

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Target IC50	K+ channel:19.9 μM

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Inhibitor, Parasite, SodiumChannel, Sodium Channel, Potassium Channel, PotassiumChannel

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Compound Identifiers

PubChem CID

16219921 ↗

Key Properties

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No computed properties available.

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