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Recombinant Cynomolgus GUCY2C Protein

SKU: orb2992727

Description

Recombinant Cynomolgus Guanylyl cyclase C is produced by our Mammalian expression system and the target gene encoding Ser24-Gln430 is expressed with a human IgG1 Fc tag at the C-terminus.

Images & Validation

Key Properties

Expression SystemHuman Cells
Biological OriginCynomolgus
Biological ActivityBLI: Loaded Anti-Human GUCY2C mAb on SA Biosensor, can bind Recombinant Cynomolgus GUCY2C (C-Fc)(Cat#orb2992727) with an affinity constant of 1.81 pM as determined in BLI assay. (Regularly tested)
TagC-Fc
Molecular WeightPredicted: 73 KDa. Observed: 90-130 KDa, reducing conditions
Expression RegionSer24-Gln430
PuritySDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Endotoxins< 1 EU/μg as determined by LAL test.

Storage & Handling

StorageLyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Form/AppearanceLyophilized
Buffer/Preservatives0.2 μm filtered solution of PBS, pH 7.4.
ReconstitutionAlways centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
Expiration Date6 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Heat-stable enterotoxin receptor; GUCY2C; STA receptor; hSTAR; Guanylyl cyclase C; GC-C; Intestinal guanylate cyclase; GUC2C; STAR; HSER; GCC; DIAR6; HSTAR; MECIL

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  • Cynomolgus GUCY2C Protein, His Tag [orb1826725]

    Unconjugated

    The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.

    The protein has a predicted molecular mass of 47.5 kDa after removal of the signal peptide.

    Mammalian

    100 μg, 50 μg, 10 μg
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Recombinant Cynomolgus GUCY2C Protein (orb2992727)

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