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Human IL-23

SKU: orb2993914

Description

Recombinant Human Interleukin-23 is produced by our Mammalian expression system and the target gene encoding Ile23-Ser328&Ala21-Pro189 is expressed with a human IgG1 Fc tag at the C-terminus.

Images & Validation

Key Properties

Expression SystemHuman Cells
Biological OriginHuman
Biological ActivityELISA: Immobilized Human IL-23R-His(Cat#orb2994303) at 5μg/ml (100 μl/well)can bind Human IL-23-Fc (Cat#orb2993914).The ED50 of Human IL-23-Fc (Cat#orb2993914) is 0.187 ug/ml.. Cell Based Assay: Measured by its ability to induce STAT reporter activity in 293F human embryonic kidney cells. The ED50 for this effect is 179.42 ng/ml.
TagC-Fc
Molecular WeightPredicted: 81.3 KDa. Observed: 80-110 KDa, reducing conditions
Expression RegionIle23-Ser328&Ala21-Pro189
PuritySDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE.
Endotoxins< 1 EU/µg as determined by LAL test.
ConjugationUnconjugated

Storage & Handling

StorageLyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Form/AppearanceLyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
ReconstitutionAlways centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
DisclaimerFor research use only

Alternative Names

SGRF; IL-23p19; CLMF p40; IL-12 subunit p40; NKSF2

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Human IL-23 (orb2993914)

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Available Sizes

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10 μg
$ 190.00
50 μg
$ 450.00
500 μg
$ 2,620.00
1 mg
$ 3,930.00
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