RecombinantFGF-9,Human

SKU: orb1494872

Description

Fibroblast Growth Factor-9 (FGF-9) is a heparin binding growth factor that belongs to the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-9 was isolated as a secreted factor that exhibits a growth-stimulating effect on cultured glial cells. In nervous system, this protein is produced mainly by neurons and may be important for glial cell development.Recombinant Human Fibroblast Growth Factor-9(rhFGF-9) produced in E.coli is a single non-glycosylated polypeptide chain containing 208 amino acids. A fully biologically active molecule, rhFGF-9 has a molecular mass of 23.4 kDa analyzed by reducing SDS-PAGE and is obtained by proprietary chromatographic techniques at GenScript.

Images & Validation

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Application Notes	Reconstituted in ddH2O at 100 μg/ml.

Key Properties

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Source	Escherichia coli.
Biological Activity	ED50 5.0× 10ˆ5 units/mg.
Molecular Weight	23.4 kDa, observed by reducing SDS-PAGE.
Protein Sequence	MAPLGEVGN YFGVQDAVPF GNVPVLPVDS PVLLSDHLGQ SEAGGLPRGP AVTDLDHLKG ILRRRQLYCR TGFHLEIFPN GTIQGTRKDH SRFGILEFIS IAVGLVSIRG VDSGLYLGMN EKGELYGSEK LTQECVFREQ FEENWYNTYS SNLYKHVDTG RRYYVALNKD GTPREGTRTK RHQKFTHFLP RPVDPDKVPE LYKDILSQS
Purification	> 95% by SDS-PAGE and HPLC analyses.
Purity	> 95% by SDS-PAGE and HPLC analyses.
Endotoxins	< 0.2 EU/μg, determined by LAL method.

Storage & Handling

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Storage	Lyophilized recombinant Human Fibroblast Growth Factor-9(rhFGF-9) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rhFGF-9 should be stable up to 2 weeks at 4°C or up to 3 months at -20°C.
Form/Appearance	Lyophilized after extensive dialysis against PBS.
Buffer/Preservatives	Lyophilized after extensive dialysis against PBS.
Disclaimer	For research use only

Alternative Names

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FGF9; Fibroblast Growth Factor-9, GAF (Glia-activating factor), HBGF-9

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