Remdesivir de(ethylbutyl 2-aminopropanoate)

SKU: orb1982914

Description

Remdesivir de(ethylbutyl 2-aminopropanoate) is a recognized impurity in Remdesivir, a nucleoside analog demonstrating potent antiviral efficacy. It exhibits EC50 values of 74 nM against SARS-CoV and MERS-CoV in human airway epithelial (HAE) cells, and 30 nM against murine hepatitis virus in delayed brain tumor cells. Notably effective in vitro against SARS-CoV-2 (COVID-19) infection, Remdesivir has garnered attention for its application in controlling the spread of the virus, as supported by references.

Research Area

Metabolism Research

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Key Properties

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CAS Number	2607871-93-0
MW	447.34
Formula	C₁₈H₁₈N₅O₇P
SMILES	Nc1ncnn2c(ccc12)[C@@]1(O[C@H](COP(O)(=O)Oc2ccccc2)[C@@H](O)[C@H]1O)C#N
Target	Drug Metabolite,Others

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Gene Symbol

Drug Metabolite,Others

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