Resolvin D5 n-3 DPA

SKU: orb3174708

Description

Resolvin D5 n-3 DPA is a specific pro-resolving lipid mediator (SPM) derived from docosapentaenoic acid (DPA). It acts as an agonist for GPR101, GPR12, and GPR84 receptors, with EC50 values of 4.6 pM, 14 pM, and 1.5 pM, respectively. This compound exhibits potent pro-resolving and anti-inflammatory properties, reducing cell adhesion on TNF-α-activated human endothelial monolayers. It significantly enhances leukocyte-targeting activity by increasing the phagocytic capacity of neutrophils and macrophages to engulf bacteria. Resolvin D5 n-3 DPA is useful for studying intestinal inflammation.

Images & Validation

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Key Properties

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CAS Number	1609382-32-2
MW	362.51
Formula	C₂₂H₃₄O₄
SMILES	[C@@H](/C=C/C=C\C/C=C\C=C\[C@H](C/C=C\CC)O)(CCCCCC(O)=O)O
Target	GPCR

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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GPCR

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