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Rhapontigenin

SKU: orb1303764

Description

Rhapontigenin is a natural stilbenoid and resveratrol analog that acts as a potent, mechanism-based inactivator of cytochrome P450 1A1 (IC50: 400 nM), inhibiting the metabolic activation of procarcinogens. It exhibits antioxidant properties and demonstrates anti-proliferative activity against various cancer cell lines, such as HL-60 and HepG2, in vitro, supporting research in chemoprevention and oncology.

Research Area

Infectious Disease & Virology, Metabolism Research

Images & Validation

Key Properties

CAS Number500-65-2
MW258.27
Purity99.72%
FormulaC15H14O4
SMILESCOc1ccc(\C=C\c2cc(O)cc(O)c2)cc1O
TargetAntifungal,Cytochromes P450,Antibacterial
SolubilityChloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.:Soluble;DMSO:131.25 mg/mL (508.19 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.74 mM)

Bioactivity

Target IC50
HL-60R:48 μM|HepG2 cells:48 μM|CYP1A1:400 nM

Storage & Handling

Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

inhibit, Fungal, hypoglycemic, Inhibitor, Bacterial, anticoagulative, antiangiogenic, antiallergic, CYPs, CYP1A1, Cytochrome P450, purgative, Rhapontigenin, Protigenin

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Key Properties

No computed properties available.

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Rhapontigenin (orb1303764)

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% DMSO +
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% Tween 80 +
%

Available Sizes

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1 mg
$ 100.00
5 mg
$ 140.00
10 mg
$ 230.00
25 mg
$ 400.00
50 mg
$ 580.00
100 mg
$ 720.00
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