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RJG-2036

SKU: orb3135362

Description

RJG-2036 is a potent covalent inhibitor of human prostaglandin reductase 2 (PTGR2) with an IC50 of 100 nM. It effectively inhibits NADPH-dependent reduction reactions, significantly reducing the secretion of inflammatory factors such as TNF-α and the release of various pro-inflammatory eicosanoids in LPS-stimulated THP-1 macrophages. RJG-2036 shows promise for research in inflammatory diseases.

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Key Properties

CAS Number2851993-73-0
MW427.48
FormulaC20H21N5O4S
SMILESO=C(C1=CC=CC(=C1)S(=O)(=O)N2N=CN=C2)N3CCN(C=4C=CC=CC4OC)CC3
TargetProstaglandin Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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RJG-2036 (orb3135362)

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