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Roemerine

SKU: orb1684257

Description

(-)-Roemerine is a natural aporphine alkaloid that acts as a Bmr inhibitor to block berberine efflux and increase membrane permeability. It has demonstrated antifungal and anticancer properties in research, with studies investigating its effects in models of fungal infection and prostate cancer.

Research Area

Infectious Disease & Virology, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number548-08-3
MW279.33
Purity99.51% (May vary between batches)
FormulaC18H17NO2
SMILES[H][C@]12Cc3ccccc3-c3c4OCOc4cc(CCN1C)c23
Target5-HT Receptor,iGluR,Antibacterial,GluR,Endogenous Metabolite,P-gp,Antibiotic
SolubilityDMSO:80 mg/mL (286.4 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (11.81 mM)

Bioactivity

In Vitro
Roemerine exhibited bactericidal effects against all tested S. aureus strains (including both methicillin-resistant and methicillin-susceptible strains), with minimum inhibitory concentrations (MICs) ranging from 32 μg/mL to 64 μg/mL.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

(-)-Roemerine, Antifection, Antibiotic, Xanthine oxidase, Roemerine

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Key Properties

No computed properties available.

Protocol Information

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1 mg
$ 140.00
5 mg
$ 360.00
DispatchUsually dispatched within 5-10 working days
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