Queen's Award Received in 2021 ISO 9001 Certified Delivered over 1,000,000 bio-reagents to life science researchers Trusted by Life Science Communities
Cart summary

You have no items in your shopping cart.

Rotigotine Hydrochloride

SKU: orb1306357

Description

Rotigotine Hydrochloride (N-0924) is a potent dopamine agonist with high selectivity for D3 receptors and demonstrated anti-Parkinsonian activity. It is approximately 50 times more potent than quinpirole in vitro. This compound is widely used in preclinical research to study dopaminergic pathways in both cellular and animal models of Parkinson's disease.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number125572-93-2
MW351.93
Purity99.66% (May vary between batches)
FormulaC19H26ClNOS
SMILESCl.CCCN(CCc1cccs1)[C@H]1CCc2c(O)cccc2C1
Target5-HT Receptor,Adrenergic Receptor,Dopamine Receptor
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.68 mM);DMSO:70 mg/mL (198.9 mM)

Bioactivity

Target IC50
α2B-adrenoceptor:27 nM (Ki)|D4 receptor:4-15 nM (Ki)|5-HT1A receptor:30 nM (Ki)|α2A-adrenoceptor:338 nM (Ki)|D5 receptor:4-15 nM (Ki)|D2 receptor:4-15 nM (Ki)|α1A-adrenoceptor:176 nM (Ki)|5-HT7 receptor:86 nM (Ki)|D3 receptor:0.71 nM (Ki)|D1 receptor:83 nM (Ki)|α1B-adrenoceptor:273 nM (Ki)

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Rotigotine, Rotigotine (Hydrochloride), Rotigotine HCl, Rotigotine Hydrochloride, Serotonin Receptor, α2B-adrenergic receptor, 5HTReceptor, 5-hydroxytryptamine Receptor, 5HT Receptor, 5-HT Receptor, Adrenergic Receptor, AdrenergicReceptor, Beta Receptor, D2, D3, D4, D5, D1, DopamineReceptor, Dopamine Receptor, Dopamine, N0923, N-0923, N0924, N-0924, N 0923, N 0924, inhibit, Inhibitor

Similar Products

Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

5 mg
$ 80.00
1 ml x 10 mM (in DMSO)
$ 80.00
10 mg
$ 100.00
25 mg
$ 130.00
50 mg
$ 160.00
100 mg
$ 210.00
200 mg
$ 280.00
DispatchUsually dispatched within 5-10 working days
Bulk Enquiry