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RP-220

SKU: orb3142659

Description

RP-220 is a peptide that targets the NLRP3 enzyme and exhibits anti-inflammatory and anti-apoptotic properties. It inhibits apoptosis of renal tubular epithelial cells caused by alkaline damage by activating the MAPK signaling pathway. In mouse models of acute kidney injury (AKI), RP-220 significantly reduces NLRP3 expression, macrophage infiltration, and renal tissue damage. Additionally, RP-220 is applicable in research on systemic lupus erythematosus (SLE) and its complication lupus nephritis (LN).

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Key Properties

TargetApoptosis,p38 MAPK,NOD-like Receptor (NLR)
Molecular Weight2308.61

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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RP-220 (orb3142659)

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