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RU-0415529

SKU: orb2945793

Description

RU-0415529 is an orally active inhibitor of SARS-CoV-2 non-structural protein 14 (NSP14), with an IC50 of 356 nM. It inhibits viral RNA methylation and replication by stabilizing the cap-binding pocket through SAH binding. Additionally, RU-0415529 exhibits anti-infective activity in mouse models.

Research Area

Epigenetics & Chromatin, Infectious Disease & Virology

Images & Validation

Key Properties

CAS Number1358734-35-6
MW419.538
FormulaC21H29N3O4S
SMILESO=C(NCC=1C=CC=CC1OC)C2=CC(=C(N2C)C)S(=O)(=O)N3CCC(C)CC3
TargetDNA Methyltransferase,SARS-CoV

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Protocol Information

RU-0415529 (orb2945793)

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