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RU-0415529

SKU: orb2945793

Description

RU-0415529 is an orally bioavailable small molecule inhibitor targeting SARS-CoV-2 NSP14 (IC50 = 356 nM). It functions by binding SAH to stabilize the cap-binding pocket, thereby inhibiting viral RNA methylation and replication. This compound has demonstrated antiviral efficacy in both biochemical assays and in vivo mouse infection models.

Research Area

Epigenetics & Chromatin, Infectious Disease & Virology

Images & Validation

Key Properties

CAS Number1358734-35-6
MW419.538
FormulaC21H29N3O4S
SMILESO=C(NCC=1C=CC=CC1OC)C2=CC(=C(N2C)C)S(=O)(=O)N3CCC(C)CC3
TargetSARS-CoV,DNA Methyltransferase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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Protocol Information

RU-0415529 (orb2945793)

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