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RWJ-58643

SKU: orb2646345

Description

RWJ-58643 is a β-trypsin and trypsin inhibitor for research on allergic inflammation. In vivo studies show it reduces nasal symptoms and IL-5 at 100 mg, but exhibits a paradoxical, dose-dependent increase in eosinophils and IL-5 at higher doses (300-600 mg).

Research Area

Protein Biochemistry

Images & Validation

Key Properties

CAS Number287183-00-0
MW446.52
FormulaC20H26N6O4S
SMILESC(C(NC(=O)[C@H]1N(C(C)=O)C[C@H](O)C1)CCCNC(=N)N)(=O)C2=NC=3C(S2)=CC=CC3
TargetSerine Protease,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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RWJ-58643 (orb2646345)

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