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(S)-Coclaurine

SKU: orb1684685

Description

(S)-Coclaurine is a natural product antagonist of nicotinic acetylcholine receptors (nAChRs), isolated from Sarcopetalum harveyanum. It is a valuable research tool for in vitro studies investigating nAChR function and pharmacology in neurobiological research.

Research Area

Neuroscience

Images & Validation

Key Properties

CAS Number486-39-5
MW285.34
Purity98.11% (May vary between batches)
FormulaC17H19NO3
SMILESC([C@H]1C=2C(=CC(OC)=C(O)C2)CCN1)C3=CC=C(O)C=C3
TargetAChR

Bioactivity

In Vitro
(+)-R-Coclaurine shows negative inotropic effects. Coclaurine derivatives and of paeoniflorin derivatives have neuromuscular blocking actions.

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

nAChR, Nicotinic acetylcholine receptors, inhibit, Inhibitor, Coclaurine, (S) Coclaurine, (S)Coclaurine, alkaloids, Calcium Channel, Tetrahydroisoquinoline

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Key Properties

No computed properties available.

Protocol Information

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10 mg
$ 310.00
DispatchUsually dispatched within 5-10 working days
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