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S1P5 receptor antagonist 1

SKU: orb3210641

Description

S1P5 receptor antagonist 1 is a selective antagonist of the S1P5 receptor that is capable of crossing the blood-brain barrier. It has an EC50 of 0.1 nM and a Ki of 4.4 nM. This compound inhibits the migration of natural killer cells towards sphingosine 1-phosphate in vitro, while having no effect on T cell migration. S1P5 receptor antagonist 1 is applicable in central nervous system disease research.

Images & Validation

Key Properties

CAS Number1621065-22-2
MW437.61
FormulaC28H39NO3
SMILESC(C=1C2=C(C(C)=CC1O[C@@H]3CC[C@@H](C(C)(C)C)CC3)C=CC=C2)N4CCC(C(O)=O)CC4
TargetLPL Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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