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S1R agonist 3

SKU: orb3211111

Description

S1R agonist 3 is a potent and selective sigma-1 receptor (S1R) agonist with a Ki of 1.5 nM. It reduces hyperactive behavior in wfs1abKO zebrafish larvae without affecting the motor skills of wild-type wfs1abWT larvae. Additionally, S1R agonist 3 can reverse learning and memory impairment induced by Aβ25-35. S1R ligand 1 is applicable for Alzheimer's disease research.

Images & Validation

Key Properties

CAS Number401501-66-4
MW253.77
FormulaC14H20ClNO
SMILESClC1=CC=C(OCCN2CCC(C)CC2)C=C1
TargetSigma receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information