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Saringosterol

SKU: orb1740616

Description

Saringosterol is a natural phytosterol exhibiting antimicrobial properties, specifically against Mycobacterium tuberculosis. It serves as a research tool for studying tuberculosis pathogenesis and evaluating potential anti-tubercular agents in both in vitro and cell-based assay systems.

Research Area

Infectious Disease & Virology, Metabolism Research

Images & Validation

Key Properties

CAS Number6901-60-6
MW428.69
Purity99.92%
FormulaC29H48O2
SMILESC[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3)C[C@@H](O)CC4)(CC1)[H])[H])(CC[C@@]2([C@@H](CCC(C(C)C)(C=C)O)C)[H])[H]
TargetLiver X Receptor,Antibacterial

Bioactivity

In Vivo
In a high-fat diet-induced Alzheimer’s disease mouse model, intraperitoneal injection of Saringosterol (10 mg/kg, every 2 days for 8 weeks) significantly increased ABCA1 and APOE expression in the hippocampus, enhanced cholesterol efflux, and improved learning and memory.
In Vitro
In RAW264.7 macrophages, Saringosterol (2-10 μM, 24 h) significantly inhibits LPS-induced production of NO and IL-6, indicating anti-inflammatory activity. In ABCA1 expression assays, Saringosterol (5 μM) activates the LXR signaling pathway and upregulates ABCA1 and ABCG1 gene expression.

Storage & Handling

Storagestore at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Cystosphaerol, Seringosterol, Saringosterol
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Key Properties

No computed properties available.

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Protocol Information

Saringosterol (orb1740616)

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Available Sizes

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1 mg
$ 340.00
5 mg
$ 770.00
10 mg
$ 1,030.00
25 mg
$ 1,560.00
50 mg
$ 2,020.00
DispatchUsually dispatched within 6-8 weeks
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