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SARS-CoV-2-IN-107

SKU: orb2945809

Description

SARS-CoV-2-IN-107 (Compound A7) is an inhibitor of SARS-CoV-2 3CLpro, with an IC50 of 261.3 nM. It inhibits the replication of SARS-CoV-2, exhibiting an EC50 of 11.7 μM. Additionally, SARS-CoV-2-IN-107 demonstrates anti-inflammatory activity in LPS-stimulated RAW264.7 macrophages, with a NO inhibition rate of 68.6%.

Research Area

Immunology & Inflammation, Infectious Disease & Virology

Images & Validation

Key Properties

MW274.244
FormulaC15H11FO4
SMILESC1=CC(=CC=C1C(=O)/C=C/C2=CC(=C(C(=C2)O)O)O)F
TargetSARS-CoV,Virus Protease,NO Synthase

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Protocol Information

SARS-CoV-2-IN-107 (orb2945809)

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