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SARS-CoV-2-IN-14

SKU: orb1689487

Description

SARS-CoV-2-IN-14 is an orally bioavailable niclosamide analogue with potent antiviral activity against SARS-CoV-2 (IC50 0.39 µM). It demonstrates improved metabolic stability in human plasma and liver S9 fractions compared to niclosamide, leading to enhanced pharmacokinetic profiles in vivo for antiviral research.

Research Area

Infectious Disease & Virology

Images & Validation

Key Properties

CAS Number22203-98-1
MW282.12
Purity99.78% (May vary between batches)
FormulaC13H9Cl2NO2
SMILESC(NC1=CC(Cl)=CC=C1)(=O)C2=C(O)C=CC(Cl)=C2
TargetSARS-CoV
SolubilityDMSO:9 mg/mL (31.9 mM)

Bioactivity

Target IC50
SARS-CoV-2:0.39 μM

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

3',5-Dichlorosalicylanilide, SARSCoV, SARS-CoV-2 3CL, SARS-CoV-2-IN-14
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Key Properties

No computed properties available.

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Protocol Information

SARS-CoV-2-IN-14 (orb1689487)

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1 ml x 10 mM (in DMSO)
$ 70.00
10 mg
$ 80.00
25 mg
$ 100.00
50 mg
$ 140.00
100 mg
$ 180.00
200 mg
$ 240.00
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