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SARS-CoV-2-IN-39

SKU: orb1819089

Description

SARS-CoV-2-IN-39 is a small molecule inhibitor with antiviral activity against SARS-CoV-2, exhibiting an EC50 of 1 μM. Its mechanism involves SKP2 inhibition and subsequent BECN1 stabilization, making it a useful research tool for studying autophagy and viral replication in vitro.

Research Area

Immunology & Inflammation, Infectious Disease & Virology

Images & Validation

Key Properties

CAS Number2882823-03-0
MW349.66
Purity99.86%
FormulaC14H8ClF4NO3
SMILESC(NC1=CC=C(OC(F)(F)F)C=C1)(=O)C2=C(O)C=C(F)C(Cl)=C2
TargetAntiviral,SARS-CoV
Solubility10% DMSO+90% Corn Oil:1.67 mg/mL (4.78 mM);DMSO:50 mg/mL (143 mM)

Bioactivity

Target IC50
SARS-CoV-2:1 μM(EC50)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Antiviral, SARSCoV, SARSCoV2IN39, SARS-CoV-2-IN-39, SARS-CoV-2, Skp2
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Key Properties

No computed properties available.

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Protocol Information

SARS-CoV-2-IN-39 (orb1819089)

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% DMSO +
%+
% Tween 80 +
%

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1 mg
$ 70.00
5 mg
$ 120.00
10 mg
$ 150.00
25 mg
$ 220.00
50 mg
$ 310.00
100 mg
$ 440.00
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