SARS-CoV-2 Mpro-IN-37

SKU: orb2945006

Description

SARS-CoV-2 Mpro-IN-37 (compound 8r) is an inhibitor of the SARS-CoV-2 main protease (Mpro), with an IC50 value of 0.0199 μM. It exhibits IC50 values of 0.00945 μM against SARS-CoV-1 Mpro and 0.111 μM against MERS-CoV Mpro. SARS-CoV-2 Mpro-IN-37 demonstrates potent antiviral activity in the nanomolar range without showing cytotoxicity.

Research Area

Infectious Disease & Virology

Images & Validation

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Key Properties

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MW	438.582
Formula	C₂₅H₃₀N₂O₃S
SMILES	O=C(N[C@@H](CC(C)C)C(N[C@@H](CC1=CC=CC=C1)C(C=C)=O)=O)CSC2=CC=CC=C2
Target	SARS-CoV

Storage & Handling

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Storage	-20°C
Disclaimer	For research use only

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Gene Symbol

SARS-CoV

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