SARS-CoV-2 PLpro-IN-1

SKU: orb2945637

Description

SARS-CoV-2 PLpro-IN-1 is a potent, non-covalent competitive inhibitor of the SARS-CoV-2 papain-like protease (PLpro), demonstrating an IC50 of 15.06 µM and a Ki of 22.93 µM. It also exhibits antiviral activity in vitro, inhibiting Vero cell proliferation with an IC50 of 7.47 µM, making it a valuable tool for studying coronavirus replication and host-pathogen interactions.

Research Area

Infectious Disease & Virology

Images & Validation

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Key Properties

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CAS Number	3053753-61-7
MW	321.376
Formula	C₁₈H₁₉N₅O
SMILES	N(C=1C2=C(C=CC(=N2)C=3C=CC(OC)=NC3)N=CC1)[C@@H]4CCNC4
Target	SARS-CoV,Virus Protease

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

172677413 ↗

Key Properties

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No computed properties available.

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