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SB 206553

SKU: orb2565320

Description

SB 206553 is a 5-HT2C inverse agonist that can attenuate methamphetamine-seeking behavior in rats. It exhibits activity for 5-HT2 receptor ligands with pKi values of 5.6 nM (5-HT2A), 7.7 nM (5-HT2B), and 7.8 nM (5-HT2C) in HEK-293 or CHO-K1 cells expressing human recombinant 5-HT2 receptors. SB 206553 can be used for research into psychostimulant abuse disorders.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number158942-04-2
MW292.34
FormulaC17H16N4O
SMILESC(NC=1C=CC=NC1)(=O)N2C=3C(=CC4=C(C3)C=CN4C)CC2
Target5-HT Receptor

Storage & Handling

Storage-20°C
DisclaimerFor research use only

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SB 206553 (orb2565320)

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