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Schisandrone

SKU: orb1684949

Description

Schisandrone (Arisantetralone C) is a 4-aryltetralone lignan isolated from Schisandra chinensis fruit. It is utilized in research for its potential neuroprotective and hepatoprotective activities, as investigated in various in vitro and in vivo experimental models.

Research Area

Immunology & Inflammation, Neuroscience, Signal Transduction

Images & Validation

Key Properties

CAS Number98619-25-1
MW356.41
Purity99.84%
FormulaC21H24O5
SMILESC[C@H]1[C@@H](C=2C(C(=O)[C@H]1C)=CC(O)=C(OC)C2)C3=CC(OC)=C(OC)C=C3
TargetBeta Amyloid,CD74,NOS,NF-κB

Bioactivity

In Vitro
To explore the effect of Schisandrone on tau protein phosphorylation in the process of differentiation of APP transgenic mouse neural stem cells into neural cells. Compared with the APP+ cell control group, cell fluorescence intensity became weak in the Schisandrone group. Phosphorylation levels of Tau[Ps262] and Tau[Ps396] were reduced, especially at Tau[Ps396] site. Phosphorylation levels of Tau[Ps262] and Tau[Ps396] were low in the APP- cell control group.

Storage & Handling

Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

NF-kB, NFkB, NFκB, NF-κB, NOS, BetaAmyloid, Beta Amyloid, bAmyloid, Arisantetralone C, b Amyloid, Schisandrone, β Amyloid, βAmyloid
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Key Properties

No computed properties available.

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Schisandrone (orb1684949)

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1 mg
$ 100.00
5 mg
$ 190.00
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