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Sempervirine nitrate

SKU: orb1991273

Description

Sempervirine nitrate is a natural alkaloid from Gelsemium elegans Benth. that suppresses hepatocellular carcinoma (HCC) proliferation and promotes apoptosis through Wnt/β-catenin pathway inhibition. It demonstrates synergistic antitumor activity with sorafenib in vivo, making it a valuable research tool for investigating HCC therapeutics.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number17994-15-9
MW335.36
FormulaC19H17N3O3
SMILESO=[N+]([O-])[O-].C12=C(NC3=C2C=C[N+]4=C3C=C(CCCC5)C5=C4)C=CC=C1
TargetWnt/beta-catenin

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Sempervirine nitrate (orb1991273)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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