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Senegenin

SKU: orb1222463

Description

Senegenin is a natural product from Polygala tenuifolia used in Chinese medicine with antioxidative and anti-inflammatory activity.

Images & Validation

Key Properties

CAS Number2469-34-3
MW537.1
Purity>98% (HPLC)
FormulaC30H45ClO6
SMILESC1[C@@H]([C@@H]([C@]([C@@H]2CC[C@]3(C4=C([C@H]5[C@@](CC4)(CCC(C5)(C)C)C(=O)O)[C@H](C[C@@H]3[C@@]12C)CCl)C)(C(=O)O)C)O)O
Targetp38 MAPK
SolubilityIn Vitro: DMSO : 100 mg/mL (186.17 mM)

Bioactivity

In Vivo
Tenuigenin (2, 4, 8 mg/kg) significantly attenuates S. aureus-induced lung histopathological changes. Tenuigenin also inhibits lung wet/dry (W/D) ratio, and inflammatory cytokines TNF-α and IL-1β production in Male BALB/c mice.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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    C30H45ClO6

    10 mg, 100 mg, 5 mg, 1 ml x 10 mM (in DMSO), 25 mg, 50 mg, 2 mg, 200 mg
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Protocol Information

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100 mg
200 mg
500 mg
10 mg
$ 190.00
25 mg
$ 340.00