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Shizukaol B

SKU: orb1681692

Description

Shizukaol B is a bioactive small molecule with anti-inflammatory and antiviral properties. It inhibits LPS-induced NO production in BV-2 microglia via JNK/AP-1 signaling and exhibits anti-HIV-1 activity against resistant strains. Additional research shows it can suppress TNF-α-stimulated monocyte adhesion to endothelial cells, supporting its study in neuroinflammation and vascular biology.

Research Area

Cell Biology, Immunology & Inflammation, Infectious Disease & Virology, Molecular Biology, Neuroscience, Pharmacology & Drug Discovery, Protein Biochemistry, Signal Transduction

Images & Validation

Key Properties

CAS Number142279-40-1
MW732.77
FormulaC40H44O13
SMILESCOC(=O)C(\C)=C1\[C@H]2C3=C(C[C@H]4[C@@]5(C)[C@@H]6C[C@@H]6[C@@]6(O)COC(=O)\C(C)=C\COC(=O)CCC(=O)OCC7=C(C[C@H]56)[C@@]24OC7=O)[C@H]2C[C@H]2[C@]3(C)[C@@H](O)C1=O
TargetTNF,HIV Protease,NO Synthase,p38 MAPK,COX,ERK,IL Receptor,Interleukin,DNA/RNA Synthesis,Prostaglandin Receptor,NF-κB,NOS,JNK

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

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Shizukaol B (orb1681692)

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