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Simepdekinra

SKU: orb3134936

Description

Simepdekinra (Compound 221) is a potent IL-17A modulator with IC₅₀ values ≤10 nM for IL-17A/A HEK-Blue cells and 10–100 nM for IL-17A/F HEK-Blue cells, suitable for studying psoriasis, ankylosing spondylitis, and psoriatic arthritis.

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Key Properties

CAS Number2978700-29-5
MW667.81
FormulaC35H50FN7O5
SMILES[C@H]([C@H](NC(=O)C=1N(CC)N=CC1)C(NC2=C(F)C=C([C@@H]([C@H](C(=O)N3C[C@@H](C)N(C)CC3)NC([C@@H](OC)C)=O)C)C=C2)=O)(C4CC4)C5CC5
TargetIL Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Simepdekinra (orb3134936)

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