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Sinapyl alcohol

SKU: orb1297147

Description

This technical grade small molecule is naturally sourced from Magnolia sieboldii. It is utilized in biochemical research for in vitro studies investigating natural product chemistry and potential bioactive properties, serving as a reference standard or experimental compound.

Research Area

Immunology & Inflammation, Neuroscience

Images & Validation

Key Properties

CAS Number537-33-7
MW210.23
Purity99.67% (May vary between batches)
FormulaC11H14O4
SMILESCOc1cc(\C=C\CO)cc(OC)c1O
TargetCOX,NOS
SolubilityDMSO:125 mg/mL (594.59 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (9.51 mM)

Bioactivity

In Vivo
Sinapyl alcohol (20,30mg/kg/day, p.o.) inhibited increased vascular permeability by acetic acid in mice and reduced acute paw edema by carrageenan in rats more so tan syringin.
In Vitro
Sinapyl alcohol more potently inhibited lipopolysaccharide (LPS)-induced nitric oxide (NO), prostaglandin E2 (PGE2), and tumor necrosis factor (TNF)-α production by macrophages than syringin. Consistent wih thse observations, the expression levels of inducible NO synthase (iNOS) and cyclooxygenase (COX)-2 was reduced by sinapyl alcohol in a concentration-dependent manner.

Storage & Handling

Storagekeep away from moisture,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

iNOS, COX-2, COX-2,iNOS, Sinapyl alcohol

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Key Properties

No computed properties available.

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Sinapyl alcohol (orb1297147)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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1 ml x 10 mM (in DMSO)
$ 70.00
25 mg
$ 90.00
50 mg
$ 120.00
100 mg
$ 170.00
500 mg
$ 370.00
DispatchUsually dispatched within 3-5 working days
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