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SJ46411-Br

SKU: orb2802368

Description

SJ46411-Br is an orally bioavailable molecular glue degrader that selectively targets CK1α by recruiting the CRL2^KLHDC2 E3 ligase. It serves as a versatile chemical tool for targeted protein degradation research and has been utilized as a core moiety in PROTAC synthesis, such as with BET inhibitors like JQ1, for probing kinase and epigenetic pathways in cellular studies.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

MW405.27
FormulaC17H13BrN2O3S
TargetLigands for E3 Ligase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information

SJ46411-Br (orb2802368)

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