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Solcitinib

SKU: orb1226801

Description

A potent, selective JAK1 inhibitor for the treatment of psoriasis, lupus, and ulcerative colitis.Psoriasis Phase 2 Clinical(In Vitro):Solcitinib is an orally active, competitive, potent, selective JAK1 inhibitor, with an IC50 of 9.8 nM, and 11-, 55- and 23-fold selectivity over JAK2, JAK3 and TYK2, respectively. Solcitinib is used in the research of moderate-to-severe plaque-type psoriasis.

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Key Properties

CAS Number1206163-45-2
MW389.4503
Purity>98% (HPLC)
FormulaC22H23N5O2
SMILESCC1(CN(C1)C(=O)C2=CC=C(C=C2)C3=CC=CC4=NC(=NN43)NC(=O)C5CC5)C
TargetJAK
SolubilityDMSO: 20 mg/mL

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

GSK-2586184 | GLPG-0778

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Solcitinib (orb1226801)

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Available Sizes

Select a size below

500 mg
2 mg
$ 90.00
5 mg
$ 130.00
10 mg
$ 160.00
25 mg
$ 230.00
50 mg
$ 290.00
100 mg
$ 450.00
200 mg
$ 710.00