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SR 12460

SKU: orb1692875

Description

SR 12460 is a small molecule that acts as an NBD mimetic, disrupting the IKKβ/NEMO interaction to inhibit NF-κB activation triggered by TNF-α or LPS. It has demonstrated efficacy in cellular assays and reduces acute pulmonary inflammation in mouse models, making it a useful research tool for studying inflammatory signaling pathways.

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Key Properties

CAS Number2055101-66-9
MW325.74
FormulaC15H14ClF2N3O
SMILESO=C(NC1=NC=C(Cl)C=C1)CNCCC=2C=C(F)C=C(F)C2
TargetOthers

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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SR 12460 (orb1692875)

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