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SR-14968

SKU: orb3211073

Description

SR-14968 is a full, allosteric, non-competitive MOR agonist with an EC50 of 88 nM for MOR in the mouse brainstem. It stabilizes MOR in a delusion-resistant G protein signaling state reversible by antagonists, and induces respiratory depression in mice. SR-14968 is applicable in pain-related research.

Images & Validation

Key Properties

CAS Number2133455-40-8
MW469.20
FormulaC20H20BrCl2N3O
SMILESO=C1NC2=CC(Cl)=C(Cl)C=C2N1C3CCN(CC3)C(C4=CC=C(Br)C=C4)C
TargetOpioid Receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information