Src Rabbit mAb [KD Validated] Antibody

SKU: orb1951705

Description

Src activity is regulated by tyrosine phosphorylation at two sites, but with opposing effects. While phosphorylation at Tyr416 in the activation loop of the kinase domain upregulates enzyme activity, phosphorylation at Tyr527 in the carboxy-terminal tail by Csk renders the enzyme less active (2).

Research Area

Signal Transduction

Images & Validation

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Item 1 of 2

Tested Applications	ICC, IHC, WB
Dilution Range	WB 1:500~1:2000 IHC 1:50~1:200 ICC/IF 1:50~1:200
Reactivity	Human, Rat

Key Properties

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Antibody Type	Recombinant Antibody
Host	Rabbit
Clonality	Monoclonal
Isotype	Rabbit IgG
Immunogen	A synthesized peptide derived from human
Purification	Affinity-chromatography
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Form/Appearance	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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EC 2.7.10.2; p60-Src; c-Src; pp60;c-src;

Quality Guarantee

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Quick Database Links

UniProt

P12931

UniProt Details

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No UniProt data available

Protocol Information

Western Blot (IB, immunoblot)

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IHC

Immunohistochemistry

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ICC

Immunocytochemistry

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Available Sizes

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50 μl

$ 260.00

100 μl

$ 340.00

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Applications:	FC, WB
Reactivity:	Human, Mouse, Rat
Species/Host:	Rabbit
Clonality:	Monoclonal
Conjugation:	Unconjugated

Applications:	FC, ICC, IHC, WB
Reactivity:	Human, Mouse, Rat
Species/Host:	Rabbit
Clonality:	Monoclonal
Conjugation:	Unconjugated

Applications:	IHC, WB
Reactivity:	Human, Mouse, Rat
Species/Host:	Rabbit
Clonality:	Monoclonal
Conjugation:	Unconjugated

Src Rabbit mAb [KD Validated] Antibody

Description

Research Area

Images & Validation

Key Properties

Storage & Handling

Alternative Names

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