(S,S)-Secoisolariciresinol diglucoside

SKU: orb1681310

Description

(S,S)-Secoisolariciresinol diglucoside ((S,S)-SDG) is a flaxseed-derived lignan exhibiting anti-inflammatory, antioxidant, and neuroprotective properties. It is utilized in research models for studying metabolic and inflammatory diseases, including obesity and osteoporosis, with applications in both in vitro and in vivo experimental systems.

Research Area

Metabolism Research

Images & Validation

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Key Properties

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CAS Number	257930-74-8
MW	686.7
Purity	99.33% (May vary between batches)
Formula	C₃₂H₄₆O₁₆
SMILES	[C@@H]([C@H](CC1=CC(OC)=C(O)C=C1)CO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)(CC3=CC(OC)=C(O)C=C3)CO[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O
Target	Antioxidant
Solubility	H2O:80 mg/mL (116.5 mM)

Bioactivity

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In Vivo	Secoisolariciresinol diglucoside (oral administration; 4 mg/mouse) administered to 10-week-old male mice 2 hours before the administration of tumor necrosis factor alpha (TNFα) significantly reduced the adhesion of leukocytes to the endothelium by 50% and the migration of leukocytes across the blood-brain barrier by 64%. Read more...
In Vitro	Secoisolariciresinol diglucoside is a major lignan component in flaxseed and exhibits potent antioxidant activity in vitro, acting as an effective scavenger of free hydroxyl radicals. Read more...

Storage & Handling

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Storage	store at low temperature,store under nitrogen \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Antioxidant, (S,S)-SDG, (S,S)-Secoisolariciresinol diglucoside, SDG, Secoisolariciresinol diglucoside

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Compound Identifiers

PubChem CID

72189390 ↗

Key Properties

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No computed properties available.

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