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STAT1/3-IN-1

SKU: orb2945210

Description

STAT1/3-IN-1 (Compound 6k) is a dual inhibitor that blocks STAT1 and STAT3 phosphorylation and nuclear translocation, while also suppressing iNOS and COX-2. It demonstrates anti-inflammatory effects in vitro by reducing IL-1β, IL-6, and TNF-α levels, making it a useful research tool for studying JAK-STAT signaling in inflammation and oncology.

Research Area

Immunology & Inflammation, Neuroscience, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number2958649-56-2
MW560.988
FormulaC28H25ClN6O5
SMILESO(C)C1=C2N(C[C@]3(N(C2=O)[C@H](C)CCO3)[H])C=C(C(NC4=CC(=CC=C4)C5=CN(N=N5)C6=C(Cl)C=CC=C6)=O)C1=O
TargetSTAT,COX,Interleukin,NO Synthase

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

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STAT1/3-IN-1 (orb2945210)

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