STING Agonist 1a

SKU: orb1692257

Description

STING agonist 1a is a cell-permeable small molecule that activates the STING pathway, inducing the expression of interferon-β and other cytokines in THP-1 cells with an EC50 of 16.77 µM. This compound is a valuable research tool for studying innate immunity, STING signaling, and related therapeutic applications in both cellular and animal models.

Research Area

Immunology & Inflammation, Pharmacology & Drug Discovery; Cell Biology

Images & Validation

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Key Properties

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CAS Number	652142-94-4
MW	396.23
Purity	98.07% (May vary between batches)
Formula	C₁₉H₁₁Cl₂N₅O
SMILES	ClC1=NC=2C=CC=CC2N3C1=NN=C3C=4C=C5C=C(OC)C=CC5=NC4Cl
Target	STING

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Compound Identifiers

PubChem CID

1002560 ↗

Key Properties

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No computed properties available.

Protocol Information

Find More Protocols

CAS Number:	2138299-68-8
MW:	779.85
Formula:	C₃₈H₄₅N₁₃O₆

CAS Number:	2228891-94-7
MW:	738.42
Formula:	C₂₁H₂₀F₂N₈Na₂O₁₁P₂S

CAS Number:	2138299-69-9
MW:	1007.89
Formula:	C₄₂H₄₇F₆N₁₃O₁₀

STING Agonist 1a

Description

Research Area

Images & Validation

Key Properties

Storage & Handling

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