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Recombinant SYP Antibody / Synaptophysin

SKU: orb2637002

Description

This recombinant mouse monoclonal antibody recognizes a protein of 38kDa that is identified as Synaptophysin. It is an N-glycosylated integral membrane protein found in neurons and endocrine cells. Synaptophysin contains four transmembrane domains and may function as a gap junction-like channel. This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely granular, cytoplasmic staining is observed, which probably correlates with the distribution of the antigen within neurosecretory vesicles. Synaptophysin is an independent, broad-range marker of neural and neuroendocrine differentiation.

Research Area

Signal Transduction

Images & Validation

Tested ApplicationsIHC-P
Dilution RangeImmunohistochemistry (FFPE): 2-4ug/ml
ReactivityHuman
Application Notes
Optimal dilution of the recombinant SYP antibody should be determined by the researcher.

Key Properties

Antibody TypePrimary Antibody
HostMouse
ClonalityRecombinant
IsotypeMouse IgG1, kappa
Clone No.rSYP/6856
ImmunogenA portion of amino acids 224-313 was used as the immunogen for the recombinant SYP antibody.
PurificationProtein A/G affinity
ConjugationUnconjugated

Storage & Handling

StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Buffer/Preservatives1 mg/ml in 1X PBS; rAlbumin free, sodium azide free
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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    IHC-P

    Human

    Mouse

    Recombinant

    Unconjugated

    100 μg, 20 μg
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UniProt Details

No UniProt data available

Protocol Information

IHC-P
Immunohistochemistry Paraffin
View Protocol

Available Sizes

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100 μg
$ 750.00
Choose Conjugation or Carrier Free Version
Free Secondary Antibody (20 ul)0/0

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