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T6167923

SKU: orb1309040

Description

T6167923 is a potent and selective small molecule inhibitor that targets the MyD88 TIR domain, blocking homodimerization and downstream NF-κB signaling. It demonstrates anti-inflammatory activity in vitro by suppressing key cytokines including IFN-γ, IL-1β, IL-6, and TNF-α. This inhibitor is a valuable research tool for studying Toll-like receptor and interleukin-1 receptor pathways in inflammatory and autoimmune disease models.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number2437475-16-4
MW458.39
Purity99.28% (May vary between batches)
FormulaC17H20BrN3O3S2
SMILESC[C@H](NC(=O)N1CCN(CC1)S(=O)(=O)c1cccc(Br)c1)c1cccs1
TargetMyD88
SolubilityDMSO:250 mg/mL (545.39 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.91 mM)

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

T 6167923, T6167923, T-6167923, MyD88

Similar Products

  • T6167923 B [orb2901699]

    >98% (HPLC)

    2437475-16-4

    458.39

    C17H20BrN3O3S2

    1 g, 500 mg, 100 mg, 2 mg, 5 mg, 10 mg, 25 mg, 50 mg
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Key Properties

No computed properties available.

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T6167923 (orb1309040)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

1 mg
$ 140.00
5 mg
$ 280.00
1 ml x 10 mM (in DMSO)
$ 310.00
10 mg
$ 410.00
25 mg
$ 680.00
50 mg
$ 900.00
100 mg
$ 1,210.00
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