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Thio-NAD

SKU: orb1980125

Description

Thio-NAD, a thione-modified derivative of the signaling molecule and enzyme cofactor NAD+, can substitute for NAD+ as a cofactor in alkaline phosphatase (ALP) enzyme activity assays. It is utilized as a substrate in dual-enzyme cycling ELISA for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein, or surface glycoprotein, and live M. tuberculosis in patient sputum. Thio-NAD is characterized by its absorbance at 405 nm, distinguishing it from other cofactors.

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Key Properties

CAS Number4090-29-3
MW679.49
FormulaC21H27N7O13P2S
SMILESNC(=S)C1CCCN(C1)C1OC(COP(O)(=O)OP(O)(=O)OCC2OC(C(O)C2O)n2cnc3c(N)ncnc23)C(O)C1O

Storage & Handling

Storage-20°C
DisclaimerFor research use only

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Thio-NAD (orb1980125)

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