Tidutamab Antibody

SKU: orb1980464

Description

Tidutamab is a humanized bispecific antibody designed for research, targeting SSTR2 on tumor cells and CD3 on T-cells to redirect immune activity. It is being investigated in preclinical and clinical studies for its antitumor potential, particularly in neuroendocrine tumors such as gastric and pancreatic models.

Research Area

Signal Transduction

Images & Validation

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Key Properties

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CAS Number	2148354-90-7
MW	197.74 kDa
Purity	97.9% (SDS-PAGE); 97.8% (SEC-HPLC)
Target	Integrin,Others

Bioactivity

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Target IC50	SSTR2+ CHO cells (human):2.2 μg/mL (ED50)
In Vivo	In NSG mice, Tidutamab was able to stimulate killing of SSTR2+ A549 lung cancer tumors by human T cells after a single intraperitoneal injection at a dose of 3 mg/kg. Read more...
In Vitro	Tidutamab was able to bind to human SSTR2+ CHO cells in the concentration range of 0-100,000 ng/mL with an ED50 value of 2.2 μg/mL and mediated the killing of SSTR2+ target cells by T cells. Read more...

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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CD3, XmAb18087, XmAb-18087

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

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Gene Symbol

Integrin,Others

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