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TLR7 agonist 18

SKU: orb3133545

Description

TLR7 agonist18 (Compound 21a) is a selective Toll-like receptor 7 (TLR7) agonist with an EC50 of 7.8 μM. It demonstrates no cytotoxicity in an HEK293 cell line co-transfected with the hTLR7 gene and can induce the secretion of several cytokines, including IL-1β, IL-12p70, IL-8, and TNF-α. This compound is useful in research related to vaccines, asthma, allergies, and cancer treatment.

Images & Validation

Key Properties

FormulaC18H16F4N4O
TargetTLR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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TLR7 agonist 18 (orb3133545)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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