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TLR7 agonist 20

SKU: orb2564387

Description

TLR7 agonist20 (compound 23) is an imidazoquinoline analogue. It acts as a potent and specific TLR7 agonist with an EC50 value of 0.23 μM for hTLR7. This compound exhibits strong adjuvant activity on spike antibody levels and induces a robust T helper cell 1 (Th1) response, increasing IgG2b and IgG2c alongside IgG1.

Research Area

Immunology & Inflammation

Images & Validation

Key Properties

CAS Number3029695-00-6
MW360.45
FormulaC22H24N4O
SMILESOCC1=CC=C(C=C1)CN2C(=NC=3C(=NC=4C=CC=CC4C32)N)CCCC
TargetTLR

Storage & Handling

Storage-20°C
DisclaimerFor research use only

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Protocol Information

TLR7 agonist 20 (orb2564387)

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