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toralactone

SKU: orb1680058

Description

Toralactone, a natural compound derived from cassia seeds, exhibits antibacterial properties against methicillin-resistant Staphylococcus aureus (MRSA). This small molecule is a valuable research tool for investigating novel anti-infective agents in both in vitro and in vivo studies.

Research Area

Immunology & Inflammation, Infectious Disease & Virology

Images & Validation

Key Properties

CAS Number41743-74-2
MW272.25
Purity98.86% (May vary between batches)
FormulaC15H12O5
SMILESO=C1OC(=CC=2C=C3C=C(OC)C=C(O)C3=C(O)C12)C
TargetNrf2,Antibacterial
SolubilityDMSO:2.73 mg/mL (10.03 mM)

Bioactivity

In Vitro
Rubrofusarin and toralactone can enhance the cytotoxic profile of P-gp substrates, such as PTX, via inhibiting P-gp efflux activity and enhancing the intracellular entrapment of P-gp substrates. Toralactone sensitize resistant MCF-7adr cell line to paclitaxel via inhibiting P-glycoprotein efflux activity.

Storage & Handling

Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Antibacterial, Keap1-Nrf2, toralactone

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Key Properties

No computed properties available.

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toralactone (orb1680058)

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(Recommended: An additional animal making an allowance for loss during the experiment)

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% DMSO +
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% Tween 80 +
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Available Sizes

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5 mg
$ 310.00
10 mg
$ 470.00
25 mg
$ 740.00
DispatchUsually dispatched within 5-10 working days
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