Transthyretin (F87M/L110M) , Human, Recombinant

SKU: orb1401961

Description

Transthyretin (TTR), formerly known as Prealbumin, is in vivo involved in the binding and transportation of the Thyroxin hormone and retinol-binding protein. Mutations in TTR are associated with familial amyloidotic polyneuropathy (FAP) which is a fatal disease characterized by amyloid depositions found in visceral organs including the heart, liver, and kidney. F87M/L110M TTR is an engineered variant unable to form a stable tetramer

Images & Validation

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Key Properties

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Source	Protein expressed in Escherichia coli
MW	13.7 kDa
Purity	95% by Chromatography and SDS-PAGE
Protein Sequence	GPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPMHEHAEVVFTANDSGPRRYTIAAMLSPYSYSTTAVVTNPKE

Storage & Handling

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Storage	Room temperature, avoid light exposure.
Form/Appearance	Lyophilized 1 mg/vial
Buffer/Preservatives	The lyophilized protein is readily soluble in PBS pH 7.4
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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