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TRPA1 agonist-3

SKU: orb3174143

Description

TRPA1 agonist-3 is a selective and orally active TRPA1 agonist, exhibiting EC50 values of 50.05 μM for human TRPA1 and 314.04 μM for mouse TRPA1 in HEK-293T cells. This compound does not activate hTRPV1, mTRPV2, hTRPV3, hTRPV4, hTRPC6, or hTRPM8 channels. Additionally, TRPA1 agonist-3 alleviates inflammatory pain in mice through channel desensitization mechanisms.

Research Area

Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number3083086-77-2
MW262.37
FormulaC14H18N2OS
SMILESN1=C(SC=C1C=2C=CC(=CC2)C)NCCCOC
TargetTRP/TRPV Channel

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information