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TS-002266

SKU: orb2664888

Description

TS-0022666 is a potent and selective inhibitor of TUT4/7 enzymes. It demonstrates anti-leukaemic and antiproliferative effects in both cellular and animal models, and its ability to reduce RNA uridylation and synergize with BCL-2 inhibitors makes it a valuable tool for investigating cancers, including those with FOCAD deficiencies.

Research Area

Cell Biology, Molecular Biology

Images & Validation

Key Properties

CAS Number2702325-64-0
MW639.53
Purity98.18%
FormulaC31H32Cl2N6O5
SMILESO=C1C=2C(N(C=C1C(O)=O)C=3C=CC(=NC3)N4CC(N(C)C)C4)=CC(=C(Cl)C2)N5[C@@H](COC6=C(Cl)C(OC)=CC=N6)CCC5
TargetDNA/RNA Synthesis
Solubility10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (5.16 mM);DMSO:80 mg/mL (125.09 mM)

Storage & Handling

Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

TS002266

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Protocol Information

TS-002266 (orb2664888)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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1 mg
$ 380.00
5 mg
$ 840.00
10 mg
$ 1,320.00
25 mg
$ 2,420.00
50 mg
$ 3,770.00
DispatchUsually dispatched within 5-10 working days
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