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Tubastatin

SKU: orb1986841

Description

Tubastatin A suppresses TGF-β1-mediated signaling by inhibiting S6K phosphorylation and the expression of HIF-1α and VEGF, while also preventing the reduction of autophagosome marker LC3B-II. This HDAC6 inhibitor is a useful research tool for studying fibrosis, cancer angiogenesis, and autophagy pathways in vitro.

Research Area

Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number1239034-70-8
MW334.41
Purity98.23%
FormulaC21H22N2O2
SMILESCOC(=O)c1ccc(Cn2c3CCN(C)Cc3c3ccccc23)cc1
TargetTGF-beta/Smad

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Smad, TGFb, TGF-b/Smad, TGFβ, TGF-β/Smad, TGFβ1, TGF-beta, TGFbeta, TGFbeta/Smad, Tubastatin TFA, Tubastatin TFA salt

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Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Key Properties

No computed properties available.

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Tubastatin (orb1986841)

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Available Sizes

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1 mg
$ 80.00
5 mg
$ 140.00
10 mg
$ 180.00
25 mg
$ 260.00
50 mg
$ 370.00
100 mg
$ 530.00
500 mg
$ 1,130.00
DispatchUsually dispatched within 5-10 working days
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