Cart summary

You have no items in your shopping cart.

U 73343

SKU: orb1218823

Description

U 73343 is an inactive analog of U 73122 and can be used as a negative control. It dose-dependently inhibits acid secretion irrespective of the stimulant. It is a phospholipase C (PLC) and 5-LO (5-lipoxygenase) inhibitor with an IC50 of 1-2.1 μM for PLC.

Images & Validation

Key Properties

CAS Number142878-12-4
MW466.66
Purity>98% (HPLC)
FormulaC29H42N2O3
SMILESO=C(CC1)N(CCCCCCN[C@H]2CC[C@@]3([H])[C@]4([H])CCC5=CC(OC)=CC=C5[C@@]4([H])CC[C@]23C)C1=O
TargetPhospholipase
SolubilityDMSO:5 mg/mL (10.71 mM; Need ultrasonic)

Bioactivity

In Vitro
U73343, which potently inhibits acid secretion, shows no inhibitory effect on either K+-pNPPase or H+, K+-ATPase activity. U73343 dose-dependently inhibits, histamine (Hist)-, carbachol (CCh)-, and dbcAMPstimulated aminopyrine accumulation in gastric glands.

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Similar Products

  • U-73343 [orb1296165]

    99.06%

    142878-12-4

    466.66

    C29H42N2O3

    2 mg, 25 mg, 1 ml x 10 mM (in DMSO), 5 mg, 10 mg, 50 mg
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at support@biorbyt.com.

Documents Download

Datasheet
Product Information
Download

Request a Document

Protocol Information

U 73343 (orb1218823)

  • Star
  • Star
  • Star
  • Star
  • Star
  • 0.0
Based on 0 reviews

Participating in our Biorbyt product reviews program enables you to support fellow scientists by sharing your firsthand experience with our products.

Login to Submit a Review

No reviews yet

Step 1: Enter information below

(Recommended: An additional animal making an allowance for loss during the experiment)

Step 2: Enter the in vivo formulation

(This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO +
%+
% Tween 80 +
%

Available Sizes

Select a size below

100 mg
200 mg
500 mg
2 mg
$ 80.00
5 mg
$ 110.00
10 mg
$ 160.00
25 mg
$ 280.00
50 mg
$ 460.00