Uracil

SKU: orb1310972

Description

Uracil is a natural pyrimidine nucleobase in RNA, where it pairs with adenine. It functions as an allosteric regulator and coenzyme in biochemical reactions and is a key precursor in synthesizing enzymes vital for cellular processes. This compound is widely used in molecular biology research, including studies on RNA metabolism, nucleotide biosynthesis, and in vitro transcription assays.

Research Area

Metabolism Research

Images & Validation

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Key Properties

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CAS Number	66-22-8
MW	112.09
Purity	99.97%
Formula	C₄H₄N₂O₂
SMILES	O=C1NC=CC(=O)N1
Target	Endogenous Metabolite
Solubility	DMSO:18.33 mg/mL (163.53 mM);H2O:< 1 mg/mL (insoluble or slightly soluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (17.84 mM);Ethanol:21 mg/mL (187.35 mM)

Bioactivity

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In Vivo

Uracil serves both as a pharmaceutical agent and as a vehicle for drug delivery. In humans and plants, uracil functions is a conformational regulator and coenzyme in various reactions. It also plays a role in the biosynthesis of polysaccharides and the transportation of aldoses. Uracil reacts with fluorine to form 5-fluorouracil, which inhibits RNA polymerase, obstructing RNA synthesis and consequently suppressing the growth of cancer cells. Within the body, uracil binds with ribose and phosphate, aiding insynthesizing enzymes essential for numerous cellular functions.

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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Endogenous Metabolite, EndogenousMetabolite, Inhibitor, inhibit, RNA, Uracil

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Compound Identifiers

PubChem CID

1174 ↗

Key Properties

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No computed properties available.

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Uracil (orb1310972)

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Applications:	ELISA, FC, ICC, IF, IHC, WB
Reactivity:	Human, Monkey, Mouse, Rat
Species/Host:	Rabbit
Clonality:	Polyclonal
Conjugation:	Unconjugated

Reactivity:	Human
Dynamic Range:	0.16-10 ng/mL
Sensitivity:	0.053 ng/mL

Reactivity:	Human
Dynamic Range:	0.16-10 ng/mL
Sensitivity:	0.049 ng/mL

Reactivity:	Human
Dynamic Range:	0.16-10 ng/mL
Sensitivity:	0.056 ng/mL

Applications:	ELISA, IF, IHC-P, WB
Predicted Reactivity:	Rat
Reactivity:	Human, Mouse
Species/Host:	Rabbit
Clonality:	Polyclonal
Conjugation:	Unconjugated

Uracil

Description

Research Area

Images & Validation

Key Properties

Bioactivity

Storage & Handling

Alternative Names

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Key Properties

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Protocol Information

Uracil (orb1310972)

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